STIs—A to Z

Sexually transmitted infections (STIs), affect people of all ages, backgrounds, and from all walks of life. As the name suggests, STIs are usually are passed on through sex—vaginal, oral or anal.

Some STIs can be spread through any contact between the penis, vagina, mouth or anus, even if there is no penetration. For example, genital herpes and human papillomavirus (HPV) can be spread through direct skin-to-skin contact—no penetration necessary. Some STIs can be spread in other ways also. For example, HIV and hepatitis B are also spread through sharing needles for injecting drugs or medicines.Knowing about STIs and how to get tested and treated is essential to taking care of your sexual health.

STIs are very common

Anyone who is sexually active can get an STI. In the U.S. alone there are approximately 20 million new cases each year. About half of these cases are in young people ages 15-24 years.

Most STIs have no symptoms

The fact that most STIs have no noticeable symptoms is one reason why the term STI is now more commonly used—a person can have an infection but no signs on any disease. So symptoms (or the lack or symptoms) is no way to judge whether you, or someone else, has an STI. The only way to know is to get tested.

Without treatment, STIs can cause severe health problems

Take chlamydia as an example. This STI is easily treated and cured with antibiotics. But if chlamydia goes untreated in a person with a uterus, it can lead to a more severe condition called pelvic inflammatory disease (PID). The uterus, fallopian tubes, and ovaries can all be damaged by untreated infection and this damage can harm future fertility (the ability to have children). In the U.S., PID is the leading cause of infertility in women.

Syphilis is another example. In the early stages of infection, syphilis can be treated and cured with antibiotics. But left untreated, syphilis can cause can cause serious, irreversibly damage and even death. Syphilis during pregnancy is also serious issue. It can cause miscarriage, stillbirth, and infant death. Babies born with syphilis can face lifelong medical issues.

All STIs are treatable

While not all STIs can be cured, they can all be treated. For example, while HIV infection can’t be cured, HIV treatment (antiretroviral therapy or ART) reduces the amount of HIV in your body and helps you stay healthy. It also helps prevent the virus from being passed on to sexual partners. Health problems can happen when STI are untreated, so getting tested regularly is important.

There are more testing options than ever before

If you have a regular health care provider, you can always ask them about STI testing. If you don’t already have a provider, you can search for a clinic that offers free or low cost testing near you. And now you can also test from the privacy of your own home, with tests conveniently delivered to you. Learn more about testing here.

A provider talks to a patient

Chlamydia is a Common and Curable Infection

Chlamydia is the most common reported bacterial STI in the U.S. It is most common in younger people—it is estimated that 1 in 20 sexually active young women aged 14-24 years has chlamydia.
A prescription bag

Are Patients Not Following Through with STI Treatment?

About 1.6 million cases of chlamydia and 600,000 cases of gonorrhea are diagnosed in the United Sates each year. A new study suggests that these patients may not be following through with STI treatment or getting the right antibiotics.
Conversations about Doxy PEP and Sexual Health

Learn More About Doxy PEP from Three People Who Take It

Many people who take doxy PEP say it gives them peace of mind in their relationships and sex life. We sat down with Oscar Alexis, Efthimios, and Maxfield Haynes to talk about doxy PEP and get their perspective.
A koala in a tree

Can Koalas Really Get Chlamydia?

On a recent episode of Love Island, a cast member sugested that we could blame our current STI epidemic on men who had sex with animals. She pointed to koalas and chlamydia as an example. There’s some truth here, but also a lot of misinformation.
NGU

NGU, or Nongonoccocal Urethritis

Nongonococcal urethritis—or NGU—is an infection of the urethra caused by germs other than gonorrhea. The most common cause is chlamydia.
Doxy-PEP works

New Studies Add to Evidence that Doxy PEP Works for STI Prevention

New studies add to our evidence that doxy PEP works to prevent bacterial STIs among transgender women and men who have sex with men.
A woman talks with her health care provider about the link between BV and chlamydia

BV and Chlamydia—New Research Shows a Possible Link

A new study found that there are two distinct types of BV infection, one of which increases the risk of chlamydia infection.
Gonorrhea

Learn About Gonorrhea and How to Prevent It

Gonorrhea (also known as “the clap”) is an infection caused by the bacteria Neisseria gonorrhoeae. It is passed on during vaginal, anal, and oral sex (performing or receiving).
A prescription bag

Are Patients Not Following Through with STI Treatment?

About 1.6 million cases of chlamydia and 600,000 cases of gonorrhea are diagnosed in the United Sates each year. A new study suggests that these patients may not be following through with STI treatment or getting the right antibiotics.
Conversations about Doxy PEP and Sexual Health

Learn More About Doxy PEP from Three People Who Take It

Many people who take doxy PEP say it gives them peace of mind in their relationships and sex life. We sat down with Oscar Alexis, Efthimios, and Maxfield Haynes to talk about doxy PEP and get their perspective.
A person receives a vaccine

Could A Vaccine You Probably Already Have Protect Against Gonorrhea? 

There’s potential good news in gonorrhea prevention as a series of studies suggests that certain meningococcal B (MenB) vaccines can reduce the risk of gonorrhea.
Doxy-PEP works

New Studies Add to Evidence that Doxy PEP Works for STI Prevention

New studies add to our evidence that doxy PEP works to prevent bacterial STIs among transgender women and men who have sex with men.
A man handed a prescription for Doxy-PEP

Doxy PEP Can Help Prevent STIs

Read through FAQa on doxy PEP is the strategy of taking the antibiotic doxycycline after condomless oral or anal sex to prevent chlamydia, gonorrhea, or syphilis.
PID is Pelvic inflammatory disease

PID is a leading cause of infertility in women

Pelvic inflammatory disease (PID) is a serious infection in the reproductive organs of women that can lead to infertility or life-threatening complications.
A newborn

Why It’s Important to Vaccinate Newborns for Hepatitis B

Experts say that vaccinating newborns against hepatitis B is one of the most important things we do to protect infants.
Hepatitis C

The 5 Main Types of Hepatitis (including 2 you can vaccinated against)

Hepatitis is an inflammation of the liver that can be caused by a group of viruses—hepatitis A, B, C, D and E. When hepatitis viruses damage liver cells, scar tissue is formed and those cells can no longer function.
An infant with a bandage where a vaccine was administered

ACIP Changes Hepatitis B Vaccination Gudiance

A committee that advises the Centers for Disease Control and Prevention (CDC) made an alarming change to the recommendations for the hepatitis B vaccine that will leave some infants unprotected.
Hepatitis C

Cure Rates for Hepatitis C “Jarringly Low”

According to new data from the Centers for Disease Control and Prevention (CDC), only one in three adults in the U.S. infected with hepatitis C have been cured despite the introduction of direct-acting antivirals almost 10 years ago.
Doctor showing something to a patient

Fast facts about HSV (Herpes Simplex Virus)

Herpes is a very common viral infection caused by herpes simplex virus (HSV). I can cause sores on the mouth or face or in the genital area. Herpes cannot be cured, but it can be treated.
Five things to know about herpes

5 Things You Should Know about Herpes

ASHA answers many questions from the public about STIs, including about herpes. Here we offer five things to know about how to manage this common infection.
Managing Herpes

Managing Herpes: The Science, The Facts, The Feelings

Managing Herpes: The Science, The Facts, The Feelings helps take the mystery out of herpes, explaining everything from diagnosis and treatment, to symptom management, to herpes and pregnancy.
USPSTF Logo

Task Force Decides Against Routine Herpes Screening

The U.S. Preventative Service Task Force (USPSTF) has advised against routine herpes screening in adolescents, adults, and pregnant women.
Doctor holding a sign that says herpes

ASHA Survey Shows Many Herpes Patients Diagnosed Incorrectly

Think you can tell that a rash or sore is a genital herpes infection just by looking at it? If you said “no,” you’re right. You can’t. And neither can your healthcare provider.
A vaccine vial and a needle

Herpes Vaccine Research

When will there be a herpes vaccine? There are currently both preventive and therapeutic vaccines under development. While the primary focus is on HSV-2, the primary cause of genital infection, HSV-2 vaccines may also have benefits in preventing or treating HSV-1 infection.
Two people holding hands on a table

Herpes Support Groups

Herpes support groups provide information and allow participants to share experiences, fears, and feelings with others who are concerned about herpes.
HIV Affects Everyone

Fast Facts about HIV

HIV stands for human immunodeficiency virus. Learn the basics about HIV prevention, testing, and treatment.
Free HIV and STI Testing

HIV Testing

The only way to tell you have HIV is get tested. HIV testing is recommended at least once for everyone, and may be recommended more often for some. Testing can be quick, easy and confidential.
A pregnant woman looks at a sonogram

HIV and Pregnancy—Take Steps to Protect Your and Your Baby

There is a lot to think about when you want to have a baby or when a baby is on the way. One important step is to learn about HIV. Knowing whether you have HIV can help you decide how to protect your baby.
HIV Treatment

People with Low Viral Loads Have Almost Zero Chance of Transmitting HIV Through Sex

A new meta-analysis of eight published studies found that the risk of sexual transmission of HIV is almost zero in people with low viral loads.
Prevent HIV

Prevent HIV

There are so many ways to prevent HIV. You can start by getting tested to learn your status.
PrEP in a pill or a shot

Should I take PrEP?

PrEP stands for pre-exposure prophylaxis. The word prophylaxis means to prevent or control the spread of an infection or disease. The goal of PrEP is to prevent HIV infection from taking hold if you are exposed to the virus.
National Gay Men's HIV/AIDS Awareness Day

Living with HIV

Life continues after becoming HIV positive. Thanks to new treatments, many people with HIV are living long, healthy lives.
An image of HPV

Human Papillomavirus (HPV)

Human papillomavirus, or HPV, is very common. Some types of HPV can cause genital warts and other types can cause cancer, including cancer of the cervix, vulva, vagina, penis or anus, as well as cancer in the back of the throat.
A child sits on her mother's lap after getting vaccinated

One and Done? New Study Suggests that One Dose of HPV Vaccine May Be Enough  

The results of large-scale study of HPV suggest that one shot of the vaccine may be enough to protect young people from HPV and related issues like cervical cancer.
A woman holds a Teal Wand, a device for at-home cervical cancer screening

FDA Approves At-Home Collection Device for Cervical Cancer Screening 

The FDA just approved the Teal Wand, a self-collection device for HPV testing that does not require a speculum exam or even a trip to the doctor’s office. People can collect their own sample at home and send it to a lab for analysis.
HPV vaccines

Is One Shot of the HPV Vaccine Enough? New Study Shows Promising Results

Is one shot enough? A recent study adds to evidence that one dose of the HPV vaccine might be enough to provide protection against cervical cancer.
HPV Awareness

Too Few People Understand the Link Between HPV and Cancer

A new study revealed a disturbing trend in health knowledge; fewer people seem to understand the connection between HPV and cancer, including cervical, oral, anal, and penile cancers.
An image of HPV

HPV-Related Cancer

According to the Centers for Disease Control and Prevention (CDC), about 36,500 cases of HPV-related cancer occur in the U.S each year.
A cure for HPV? Fact or fake

A Cure for HPV? Evaluating HPV Treatment Options

A so-called "cure for HPV" can sound impressive, but bold claims don't mean products have been through necessary research to ensure that they are safe and effective. Learn how to distinguish between facts and hype.
Syphilis can be cured

Understanding Syphilis and How to Prevent It

Syphilis can be treated more easily if it is caught early. But undiagnosed and untreated syphilis can be dangerous. It can cause irreversible health damage and even death.
Conversations about Doxy PEP and Sexual Health

Learn More About Doxy PEP from Three People Who Take It

Many people who take doxy PEP say it gives them peace of mind in their relationships and sex life. We sat down with Oscar Alexis, Efthimios, and Maxfield Haynes to talk about doxy PEP and get their perspective.
A pregnant patient at a doctor's appointment

Report Highlights Missed Opportunities for Congenital Syphilis Prevention

A report from the Centers for Disease Control (CDC) shows that we’re missing opportunities to prevent congenital syphilis and save lives.
A needle with syphilis treatment

A Drug Recall May Mean a Another Shortage of Syphilis Treatment

An antibiotic that is important in the fight against syphilis will once again be hard to find, this time because of a voluntary recall by the manufacturer.
A needle is inserted into a vial

One Dose of Penicillin Found Effective for Syphilis 

A new study found that a single shot of benzathine penicillin G (BPG) treated early syphilis as well as the standard three-injection regimen.
Maternity Care Deserts

Federal Government Invests $4 Million to Prevent Syphilis in Newborns 

The U.S. Department of Health and Human Services (HHS) is investing $4 million to expand rapid syphilis testing. The goal is to find and treat more cases of syphilis during pregnancy to prevent syphilis in newborns and its complications.
Doxy-PEP works

New Studies Add to Evidence that Doxy PEP Works for STI Prevention

New studies add to our evidence that doxy PEP works to prevent bacterial STIs among transgender women and men who have sex with men.
Trichomoniasis

Trichomoniasis (a.k.a. “Trich)

With roughly two million cases in the U.S., trichomoniasis (“trich”) is the most common STI you’ve never heard of. Learn more about this common STI in our four-part expert series.
Healthy vaginas

Vaginal Health

What keeps a vagina healthy? Like many things in life, it’s all about balance. What's important is to know what's normal and when things may be off—and when to seek care.
Swab test for chlamydia, gonorrhea, and trich

FDA Approves a New At-Home Test for Three Common STIs

The FDA just approved a new, fully at-home test for chlamydia, gonorrhea, and trichomoniasis. The tests, which is only for women, will be available without a prescription. Users can collect their own sample and have results in less than 30 minutes.
NGU

NGU, or Nongonoccocal Urethritis

Nongonococcal urethritis—or NGU—is an infection of the urethra caused by germs other than gonorrhea. The most common cause is chlamydia.
Mgen

MGen: The STI You’ve (Probably) Never Heard Of

Mycoplasma genitalium, or Mgen, was first identified in 1981. It is a bacterium that can infect the reproductive tract and is passed on through sexual contact.
Molluscum A sample is viewed under a microscope

Molluscum Contagiosum

Molluscum contagiosum is a skin disease caused by the molluscum contagiosum virus (MCV) Once a disease primarily of children, molluscum has evolved to become a sexually transmitted infection in adults.
A person with lesions on their abdomen from scabies

Scabies

Scabies is an infestation of the top layer of skin caused by the parasite. Scabies are passed on through close physical contact. Transmission is more likely when partners spend the night together than during a brief sexual encounter.
Pubic lice or crabs

Crabs (a.k.a. Pubic Lice) usually don’t cause anything more than discomfort and inconvenience

Pubic lice, also known as crabs, are small parasites that are usually found on the pubic hair. Symptoms of crabs can be bothersome, but in general crabs don't cause anything more than discomfort and inconvenience.